![]() ![]() Prior to the introduction of the space ball probe, stereological estimators of length were plagued by the requirement for an isotropic interaction between the area probes and linear features such as axons and capillaries. ![]() The stereological relationship formula for estimating length density, L V ^ = 2 Structural parameters of potential interest and for which quantitative studies of length have yet to be carried out include microtubules, involved in intracellular transport, and neuropil threads, an expression of Alzheimer's disease. These parameters can be used to evaluate brain hemodynamics ( Kubíková et al., 2018), tissue oxygenation ( Nikolajsen et al., 2015), and tissue repair ( Lee et al., 2005 McConnell et al., 2016) and ultimately used to develop therapeutic approaches to brain disorders. Examples using space ball probes include the length of dopaminergic axons, which can be related to the dopaminergic innervation and function of the striatum ( Li et al., 2016) the length of serotoninergic ( Liu et al., 2011) and cholinergic axons in cerebral cortex which can be related to cortical function ( Nikolajsen et al., 2011) and the length of astrocyte processes, which can be related to immune-reactivity ( McNeal et al., 2016). Estimates of the length of cellular features can provide quantitative information about various biological functions. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |